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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WIPF1
All Species:
32.42
Human Site:
Y455
Identified Species:
59.44
UniProt:
O43516
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43516
NP_001070737.1
503
51275
Y455
D
E
W
E
S
R
F
Y
F
H
P
I
S
D
L
Chimpanzee
Pan troglodytes
XP_001150374
510
51924
Y455
D
E
W
E
S
R
F
Y
F
H
P
I
S
D
L
Rhesus Macaque
Macaca mulatta
XP_001090880
510
52064
Y455
D
E
W
E
S
R
F
Y
F
H
P
I
S
D
L
Dog
Lupus familis
XP_545531
517
52682
Y469
D
E
W
E
S
R
F
Y
F
H
P
I
S
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1I7
493
50062
Y445
D
E
W
E
S
R
F
Y
F
H
P
I
S
D
L
Rat
Rattus norvegicus
Q6IN36
487
49732
Y439
D
E
W
E
S
R
F
Y
F
H
P
I
S
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515714
498
50998
Y450
D
E
W
E
S
R
F
Y
F
H
P
V
S
D
L
Chicken
Gallus gallus
NP_001012935
494
49866
S446
D
E
W
E
S
R
F
S
F
H
P
I
S
D
L
Frog
Xenopus laevis
NP_001079978
426
44520
Y386
K
D
D
F
E
S
K
Y
S
F
H
S
V
D
D
Zebra Danio
Brachydanio rerio
XP_001919866
485
49016
R440
W
E
S
R
F
T
F
R
P
V
S
D
L
P
P
Tiger Blowfish
Takifugu rubipres
NP_001098701
410
41639
P370
F
H
P
A
S
D
F
P
P
P
E
P
Y
I
P
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001195725
392
41038
R351
D
D
F
E
S
R
F
R
F
N
S
S
S
R
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P37370
817
82575
P477
V
T
P
G
G
P
L
P
F
L
A
E
I
Q
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
96.6
85.8
N.A.
88.6
87.4
N.A.
80.9
73.1
40.5
58.6
39.3
N.A.
N.A.
N.A.
35.9
Protein Similarity:
100
98.2
97.6
90.3
N.A.
92
91.6
N.A.
87.2
82.1
50.5
68.1
48.3
N.A.
N.A.
N.A.
42.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
93.3
13.3
13.3
13.3
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
20
13.3
13.3
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
70
16
8
0
0
8
0
0
0
0
0
8
0
70
8
% D
% Glu:
0
70
0
70
8
0
0
0
0
0
8
8
0
0
0
% E
% Phe:
8
0
8
8
8
0
85
0
77
8
0
0
0
0
8
% F
% Gly:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
62
8
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
54
8
8
0
% I
% Lys:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% K
% Leu:
0
0
0
0
0
0
8
0
0
8
0
0
8
0
62
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
16
0
0
8
0
16
16
8
62
8
0
8
16
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
8
0
70
0
16
0
0
0
0
0
8
0
% R
% Ser:
0
0
8
0
77
8
0
8
8
0
16
16
70
0
0
% S
% Thr:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% T
% Val:
8
0
0
0
0
0
0
0
0
8
0
8
8
0
0
% V
% Trp:
8
0
62
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
62
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _